# autogen vs ruflo
_Agent Frameworks · independent comparison_

> autogen and ruflo are both open-source agent frameworks you can self-host for free. autogen is written primarily in Python; ruflo in TypeScript. Neither is universally better — pick by fit.

## Side by side

**autogen**
- Open source · Framework · 60k★ · Python · CC-BY-4.0 · active 3 months ago
- Best for: Research-grade multi-agent conversation patterns backed by Microsoft.
- Avoid if: You need a stable, minimal API for simple single-agent tasks.
- [listing](https://agentsearchengine.app/agents/autogen) · [official](https://microsoft.github.io/autogen/)

**ruflo**
- Open source · Framework · 67k★ · TypeScript · MIT · active 1 day ago
- Best for: Adding tools, memory, loops, and sandboxes on top of Claude Code or Codex.
- Avoid if: You do not already use Claude Code or Codex — Ruflo is a harness layered on them.
- [listing](https://agentsearchengine.app/agents/ruflo) · [official](https://Cognitum.One)

## Key differences

- autogen is written primarily in Python; ruflo in TypeScript.
- Licensing differs: autogen is CC-BY-4.0, ruflo is MIT.

## Which to choose

**Choose autogen if:** Research-grade multi-agent conversation patterns backed by Microsoft.

**Choose ruflo if:** Adding tools, memory, loops, and sandboxes on top of Claude Code or Codex.

## FAQ

**What's the main difference between autogen and ruflo?**
autogen is written primarily in Python; ruflo in TypeScript.

**Is autogen or ruflo better?**
Neither is universally better. autogen is the stronger fit for Research-grade multi-agent conversation patterns backed by Microsoft; ruflo for Adding tools, memory, loops, and sandboxes on top of Claude Code or Codex. Use the side-by-side specs to decide by your own constraints.

**Is autogen or ruflo free?**
autogen is free to run and self-host; ruflo is free to run and self-host. Both are free to self-host — you only pay for the infrastructure and any model or API usage.

**Which is more popular, autogen or ruflo?**
By GitHub stars — a proxy for open-source adoption — ruflo is ahead (67k vs 60k). Stars measure attention, not necessarily the better fit for you.

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Source: [Agent Search Engine](https://agentsearchengine.app) — https://agentsearchengine.app/compare/autogen-vs-ruflo