Open source · Python
Best Python AI agents
The 166 open-source AI agents written in Python in this index, ranked by real maintained adoption (GitHub stars and recent commit activity), never by sponsorship. Hermes Agent leads the set at 249,707 GitHub stars, and 135 of the 166 have shipped a commit in the last 90 days. Every project here is Python-first, self-hostable, and free to run; the trade-off is you host and maintain it yourself. Right now it's led by Hermes Agent (250k stars), with AutoGPT and Langflow close behind. Rankings shift as projects gain stars and ship commits.
Hermes AgentAgentNous Research's self-improving AI agent that builds skills from experience and remembers you across sessions.Open sourcePython · MITVerified · Active 250kGitHub starsAutoGPTAgentAutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.Open sourcePythonVerified · Active 188kGitHub starsLangflowPlatformA visual builder for AI agents and workflows that deploys each flow as an API or an MCP server.Open sourcePython · MITVerified · Active 155kGitHub starslangchainFrameworkThe agent engineering platform.Open sourcePython · MITVerified · Active 147kGitHub starsBrowser UseAgentA Python agent framework for interacting with websites through a browser.Open sourcePython · MITVerified · Active 117kGitHub starsScraplingInfrastructureAn adaptive Web Scraping framework that handles everything from a single request to a full-scale crawl!Open sourcePython · BSD-3-ClauseVerified · Active 84kGitHub starsdeer-flowAgentAn open-source long-horizon SuperAgent harness that researches, codes, and creates.Open sourcePython · MITVerified · Active 83kGitHub starsMetaGPTFrameworkA multi-agent framework that assigns software-company roles to LLM agents to turn a requirement into a project.Open sourcePython · MITVerified 71kGitHub starsmem0InfrastructureUniversal memory layer for AI AgentsOpen sourcePython · Apache-2.0Verified · Active 66kGitHub starsTrendRadarAgentAI-driven public opinion & trend monitor with multi-platform aggregation, RSS, and smart alerts.Open sourcePython · GPL-3.0Verified · Active 63kGitHub starsautogenFrameworkA programming framework for agentic AI; upstream is in maintenance mode.Open sourcePython · CC-BY-4.0Verified 61kGitHub starscrewAIFrameworkFramework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.Open sourcePython · MITVerified · Active 59kGitHub stars
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nanobotAgentLightweight, open-source AI agent for your tools, chats, and workflows.Open sourcePython · MITVerified · Active 49kGitHub starsCowAgentAgentOpen-source super AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-model, multi-channel. Lightweight, extensible, one-line install.Open sourcePython · MITVerified · Active 47kGitHub starsLangGraphFrameworkLangChain's low-level orchestration framework for stateful, controllable agents.Open sourcePython · MITVerified · Active 42kGitHub starsagnoAgentBuild, run, and manage agent platforms.Open sourcePython · Apache-2.0Verified · Active 42kGitHub starsBettaFishAgentA multi-agent public-opinion analysis assistant anyone can use -- reconstructs the real shape of public sentiment and forecasts where it is heading. Built from scratch, no framework dependencies.Open sourcePython · GPL-2.0Verified · Active 42kGitHub starswshobson/agentsPlatformMulti-harness agentic plugin marketplace for Claude Code, Codex CLI, Cursor, OpenCode, GitHub Copilot, and Gemini CLIOpen sourcePython · MITVerified · Active 40kGitHub starsDSPyFrameworkStanford's framework for programming, not prompting, language models, with optimisers for prompts and weights.Open sourcePython · MITVerified · Active 38kGitHub starskhojAgentYour AI second brain. Self-hostable. Get answers from the web or your docs. Build custom agents, schedule automations, do deep research.Open sourcePython · AGPL-3.0Verified 38kGitHub starsAgentScopeFrameworkA production-ready Python agent framework built around model reasoning and tool use rather than rigid orchestration.Open sourcePython · Apache-2.0Verified · Active 33kGitHub starsstormAgentAn LLM-powered knowledge curation system that researches a topic and generates a full-length report with citations.Open sourcePython · MITVerified 32kGitHub starsGraphitiInfrastructureA framework for building temporal context graphs that give AI agents memory of how facts change.Open sourcePython · Apache-2.0Verified · Active 31kGitHub starsCogneeInfrastructureAn open-source memory platform that turns documents, code and conversations into a knowledge graph for agents.Open sourcePython · Apache-2.0Verified · Active 31kGitHub starsserenaSDK / libraryA powerful MCP toolkit for coding, providing semantic retrieval and editing capabilities - the IDE for your agentOpen sourcePython · MITVerified · Active 30kGitHub starsOpenAI Agents SDK (Python)FrameworkOpenAI's lightweight, provider-agnostic Python framework for multi-agent workflows.Open sourcePython · MITVerified · Active 30kGitHub starsgpt-researcherAgentAn autonomous agent that conducts deep research on any data using any LLM providersOpen sourcePython · Apache-2.0Verified · Active 30kGitHub starsMCP for Blender (blender-mcp)MCP serverConnect Blender to Claude or any LLM client for prompt-driven 3D modelling and scene editing.Open sourcePython · MITVerified · Active 30kGitHub starsfastmcpSDK / libraryThe fast, Pythonic way to build MCP servers and clients.Open sourcePython · Apache-2.0Verified · Active 28kGitHub starsagenticSeekAgentFully Local Manus AI. No APIs, No $200 monthly bills. Enjoy an autonomous agent that thinks, browses the web, and code for the sole cost of electricity.Open sourcePython · GPL-3.0Verified · Active 27kGitHub starscuaInfrastructureOpen-source infrastructure for Computer-Use Agents. Sandboxes, SDKs, and benchmarks to train and evaluate AI agents that can control full desktops (macOS, Linux, Windows).Open sourcePython · MITVerified · Active 27kGitHub starshaystackFrameworkOpen-source AI orchestration framework for building context-engineered, production-ready LLM applications.Open sourcePython · Apache-2.0Verified · Active 27kGitHub starsMCP Python SDK (official)SDK / libraryThe official Python SDK for building MCP servers and clients.Open sourcePython · MITVerified · Active 24kGitHub starsskyvernAgentAutomate browser based workflows with AIOpen sourcePython · AGPL-3.0Verified · Active 23kGitHub starsMaxKBPlatformMaxKB is an open-source platform for building enterprise-grade agents.Open sourcePython · GPL-3.0Verified · Active 23kGitHub starsOpikInfrastructureComet's open-source platform for LLM and agent tracing, evaluation, prompt management and monitoring.Open sourcePython · Apache-2.0Verified · Active 22kGitHub starsAgent Development Kit (Google ADK)FrameworkGoogle's open-source, code-first Python framework for building, evaluating and deploying AI agents.Open sourcePython · Apache-2.0Verified · Active 22kGitHub starsFunASRSDK / libraryIndustrial-grade speech recognition toolkit: 170x realtime, 50+ languages, speaker diarization, emotion detection, streaming, and OpenAI-compatible API.Open sourcePython · MITVerified · Active 21kGitHub starspydantic-aiFrameworkAI Agent Framework, the Pydantic wayOpen sourcePython · MITVerified · Active 20kGitHub starsDeepResearchAgentTongyi Deep Research, the Leading Open-source Deep Research AgentOpen sourcePython · Apache-2.0Verified 20kGitHub starsCAMELFrameworkAn open-source multi-agent framework from the CAMEL-AI community for studying and building agent societies.Open sourcePython · Apache-2.0Verified · Active 18kGitHub starsSuperAGIFramework<> SuperAGI - A dev-first open source autonomous AI agent framework. Enabling developers to build, manage & run useful autonomous agents quickly and reliably.Open sourcePython · MITVerified 18kGitHub starsPipecatFrameworkCompose voice and multimodal agents with Python processing pipelines.Open sourcePython · BSD-2-ClauseVerified · Active 16kGitHub starsSkill_SeekersSDK / libraryConvert documentation websites, GitHub repositories, and PDFs into Claude AI skills with automatic conflict detectionOpen sourcePython · MITVerified · Active 15kGitHub starsLiveKit AgentsFrameworkBuild voice and multimodal agents that participate in LiveKit rooms.Open sourcePython · Apache-2.0Verified · Active 14kGitHub starsE2BInfrastructureOpen-source infrastructure for running AI-generated code in secure, isolated cloud sandboxes.Open sourcePython · Apache-2.0Verified · Active 14kGitHub starsagent-frameworkFrameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and.NET.Open sourcePython · MITVerified · Active 14kGitHub starstxtaiFrameworkAn all-in-one Python framework for semantic search, LLM orchestration and language-model workflows.Open sourcePython · Apache-2.0Verified · Active 13kGitHub starsAgent-SFrameworkAgent S: an open agentic framework that uses computers like a humanOpen sourcePython · Apache-2.0Verified · Active 12kGitHub starsida-pro-mcpMCP serverAI-powered reverse engineering assistant that bridges IDA Pro with language models through MCP.Open sourcePython · MITVerified · Active 12kGitHub starshexstrike-aiMCP serverHexStrike AI MCP Agents is an advanced MCP server that lets AI agents (Claude, GPT, Copilot, etc.) autonomously run 150+ cybersecurity tools for automated pentesting, vulnerability discovery, bugOpen sourcePython · MITVerified 12kGitHub starsfastapi_mcpSDK / libraryExpose your FastAPI endpoints as Model Context Protocol (MCP) tools, with Auth!Open sourcePython · MITVerified 12kGitHub starsPAL MCP (formerly Zen MCP)MCP serverLet Claude Code, Gemini CLI or Codex CLI consult other models and spawn CLI subagents from one session.Open sourcePython · Apache-2.0Verified 12kGitHub starshiveFrameworkMulti-Agent Harness for Production AIOpen sourcePython · Apache-2.0Verified · Active 11kGitHub starsBinduInfrastructureBindu: The identity, communication, and payments layer for AI agents.Open sourcePythonVerified · Active 9.8kGitHub starsAWS MCP ServersMCP serverOpen source MCP Servers for AWSOpen sourcePython · Apache-2.0Verified · Active 9.7kGitHub starslocal-deep-researchAgent~95% on SimpleQA (e.g. Qwen3.6-27B on a 3090). Supports all local and cloud LLMs (llama.cpp, Ollama, Google,...). 10+ search engines - arXiv, PubMed, your private documents.Open sourcePython · MITVerified · Active 9.1kGitHub starsmcp-agentFrameworkA composable Python framework for building agents from MCP servers and simple workflow patterns.Open sourcePython · Apache-2.0Verified 8.6kGitHub starsharness-sdkSDK / libraryBuild an agent harness and control it end-to-end. Open-source SDK for production AI agents in Python & TypeScript - any model, any cloud.Open sourcePython · Apache-2.0Verified · Active 8.5kGitHub starsMiroThinkerAgentMiroThinker is a deep research agent optimized for complex research and prediction tasks. Our latest models, MiroThinker-1.7, achieves 74.0 and 75.3 on the BrowseComp and BrowseComp Zh, respectively.Open sourcePython · Apache-2.0Verified 8.4kGitHub starsdeep-searcherAgentOpen Source Deep Research Alternative to Reason and Search on Private Data. Written in Python.Open sourcePython · Apache-2.0Verified · Active 8.3kGitHub starsShortGPTFrameworkShortGPT - Experimental AI framework for youtube shorts / tiktok channel automationOpen sourcePython · MITVerified 8.0kGitHub starsUpsonicFrameworkBuild autonomous AI agents in Python.Open sourcePython · MITVerified 8.0kGitHub starsopenevolveAgentOpen-source implementation of AlphaEvolveOpen sourcePython · Apache-2.0Verified · Active 7.5kGitHub starsWindows-MCPMCP serverLet AI agents operate Windows: open apps, control windows, click and type, and read UI state.Open sourcePython · MITVerified · Active 7.4kGitHub starsunstractPlatformLLM-Driven Extraction of Unstructured Data — Built for API Deployments & ETL Pipeline WorkflowsOpen sourcePython · AGPL-3.0Verified · Active 7.3kGitHub starsSwarmsFrameworkA Python multi-agent orchestration framework with prebuilt sequential, concurrent and hierarchical architectures.Open sourcePython · Apache-2.0Verified · Active 7.2kGitHub starsintentkitFrameworkIntentKit is an open-source, self-hosted cloud agent cluster that manages a collaborative team of AI agents for you.Open sourcePython · MITVerified · Active 6.5kGitHub starsagent-governance-toolkitSDK / libraryAI Agent Governance Toolkit — Policy enforcement, zero-trust identity, execution sandboxing, and reliability engineering for autonomous AI agents. Covers 10/10 OWASP Agentic Top 10.Open sourcePython · MITVerified · Active 6.4kGitHub starsAtomic AgentsFrameworkA lightweight, modular Python framework for building agent pipelines from small, composable pieces.Open sourcePython · MITVerified · Active 6.3kGitHub starsfaraAgentFara-7B: An Efficient Agentic Model for Computer UseOpen sourcePython · MITVerified · Active 6.2kGitHub starssembleSDK / libraryFast and Accurate Code Search for Agents. Uses ~98% fewer tokens than grep+readOpen sourcePython · MITVerified · Active 6.2kGitHub starsAIO SandboxInfrastructureAn all-in-one Docker sandbox for AI agents with a browser, shell, files, VS Code server, Jupyter and MCP.Open sourcePython · Apache-2.0Verified · Active 6.0kGitHub starsagents-cliAgentThe CLI and skills that turn any coding assistant into an expert at creating, evaluating, and deploying AI agents on Google Cloud.Open sourcePython · Apache-2.0Verified · Active 6.0kGitHub starsagentsFrameworkAn Open-source Framework for Data-centric, Self-evolving Autonomous Language AgentsOpen sourcePython · Apache-2.0Verified 6.0kGitHub starsMCP Atlassian (community)MCP serverA community MCP server for Jira and Confluence that supports both Cloud and Server/Data Center.Open sourcePython · MITVerified · Active 5.9kGitHub starsrllmFrameworkDemocratizing Reinforcement Learning for LLMsOpen sourcePython · Apache-2.0Verified · Active 5.8kGitHub starsklavisInfrastructureKlavis AI: MCP integration platforms that let AI agents use tools reliably at any scaleOpen sourcePython · Apache-2.0Verified 5.8kGitHub starsZotero MCPMCP serverSearch, read and annotate your Zotero research library from Claude, ChatGPT and other MCP clients.Open sourcePython · MITVerified · Active 5.2kGitHub starsag2FrameworkAG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3xOpen sourcePython · Apache-2.0Verified · Active 5.0kGitHub starsHome Assistant MCP (ha-mcp)MCP serverAn unofficial, comprehensive MCP server for controlling devices and managing automations in Home Assistant.Open sourcePython · MITVerified · Active 4.9kGitHub starsDeepAnalyzeAgentDeepAnalyze is the first agentic LLM for autonomous data science.Open sourcePython · MITVerified · Active 4.7kGitHub starsyoutu-agentFrameworkA simple yet powerful agent framework that delivers with open-source modelsOpen sourcePythonVerified 4.6kGitHub starsContextForge (IBM MCP Context Forge)InfrastructureIBM's open-source gateway and registry that federates MCP, A2A and REST/gRPC APIs behind one governed endpoint.Open sourcePython · Apache-2.0Verified · Active 4.5kGitHub starsMCP Server for Obsidian (mcp-obsidian)MCP serverRead, search, append to and patch notes in an Obsidian vault from an MCP client.Open sourcePython · MITVerified · Active 4.4kGitHub starsgptmeAgentA provider-agnostic personal AI agent for the terminal, with shell, Python, web and vision tools.Open sourcePython · MITVerified · Active 4.4kGitHub starsms-agentFrameworkMS-Agent: a lightweight framework to empower agentic execution of complex tasksOpen sourcePython · Apache-2.0Verified · Active 4.4kGitHub starsmcpoInfrastructureA simple, secure MCP-to-OpenAPI proxy serverOpen sourcePython · MITVerified 4.4kGitHub starsCodeGraphContextMCP serverIndex a local codebase into a graph database and query its call chains from AI assistants over MCP.Open sourcePython · MITVerified · Active 4.2kGitHub starsexcel-mcp-serverMCP serverA Model Context Protocol server for Excel file manipulationOpen sourcePython · MITVerified · Active 4.2kGitHub starsLangroidFrameworkA lightweight Python framework for multi-agent LLM applications, from CMU and UW-Madison researchers.Open sourcePython · MITVerified · Active 4.1kGitHub starsBasic MemoryMCP serverPersistent AI memory as local Markdown files that both you and the model can read and edit.Open sourcePython · AGPL-3.0Verified · Active 4.1kGitHub starsfast-agentFrameworkCode, Build and Evaluate agents - excellent Model and Skills/MCP/ACP/A2A SupportOpen sourcePython · Apache-2.0Verified · Active 3.9kGitHub starsclaude_codex_bridgeAgentVisible multi-agent CLI workspace for mixing Codex, Claude, Gemini, Kimi, Qwen, Cursor, Copilot, Pi, OpenCode, and other AI coding agentsOpen sourcePythonVerified · Active 3.5kGitHub starsVibe-SkillsSDK / libraryVibe-Skills is an all-in-one AI skills package.Open sourcePython · Apache-2.0Verified · Active 3.5kGitHub starsBeeAI FrameworkFrameworkA framework for production-ready multi-agent systems with matching Python and TypeScript libraries.Open sourcePython · Apache-2.0Verified · Active 3.4kGitHub starsPostgres MCP ProMCP serverA Postgres MCP server with index tuning, EXPLAIN plans, health checks and configurable safe SQL execution.Open sourcePython · MITVerified 3.3kGitHub starsGoogle Analytics MCP ServerMCP serverGoogle's experimental MCP server for querying Google Analytics accounts, reports and realtime data.Open sourcePython · Apache-2.0Verified 3.3kGitHub starsGoogle Workspace MCP ServerMCP serverNatural-language control of Gmail, Calendar, Drive, Docs, Sheets, Slides, Forms, Tasks, Contacts and Chat.Open sourcePython · MITVerified · Active 3.2kGitHub starsDaVinci Resolve MCP ServerMCP serverLet AI assistants control DaVinci Resolve Studio through its official scripting API: edit, organise, grade and render.Open sourcePython · MITVerified · Active 3.2kGitHub starsArXiv MCP ServerMCP serverA local MCP server for reading arXiv papers section by section from their original LaTeX, with BibTeX and topic watches.Open sourcePython · Apache-2.0Verified · Active 3.2kGitHub starsTuriX-CUAAgentThis is the official website for TuriX Computer-use-AgentOpen sourcePython · MITVerified · Active 3.2kGitHub starsAbleton MCPMCP serverControl Ableton Live from Claude and other MCP clients: create tracks, arrange clips and edit sessions.Open sourcePython · MITVerified · Active 3.1kGitHub starsMiroFlowFrameworkTop-1 on 5+ benchmarks | Web UI | Supports MiroThinker, Claude, Kimi, OpenAIOpen sourcePython · Apache-2.0Verified 3.1kGitHub starsSnyk Agent ScanInfrastructureDiscover and scan the agents, MCP servers and skills on your machine for prompt injection and vulnerabilities.Open sourcePython · Apache-2.0Verified · Active 3.1kGitHub starsteaql-agent-kitSDK / libraryDeterministic execution for non-deterministic AI.Open sourcePython · MITVerified · Active 2.8kGitHub starsmcp-proxyInfrastructureBridge MCP transports: run a remote SSE or streamable HTTP server over stdio, or expose a stdio server over HTTP.Open sourcePython · MITVerified 2.8kGitHub starsAgent Toolkit for AWSMCP serverAWS's official MCP servers, skills and plugins that help coding agents build and deploy on AWS.Open sourcePython · Apache-2.0Verified · Active 2.7kGitHub starscocoindex-codeSDK / libraryA super light-weight embedded code search engine CLI (AST based) that just works - saves 70% token and improves speed for coding agent Star if you like it!Open sourcePython · Apache-2.0Verified · Active 2.7kGitHub starsPaper Search MCPMCP serverSearch and download academic papers from arXiv, PubMed, bioRxiv, Semantic Scholar and many more sources.Open sourcePython · MITVerified · Active 2.7kGitHub starsFreeCAD MCPMCP serverControl FreeCAD from Claude Desktop and other MCP clients: create models, run scripts and FEM analyses.Open sourcePython · MITVerified · Active 2.5kGitHub starsKiCAD MCP ServerMCP serverDesign printed circuit boards in KiCAD with Claude and other LLMs through natural language.Open sourcePython · MITVerified · Active 2.5kGitHub starsverl-agentFrameworkverl-agent is an extension of veRL, designed for training LLM/VLM agents via RL. verl-agent is also the official code for paper "Group-in-Group Policy Optimization for LLM Agent Training"Open sourcePython · Apache-2.0Verified 2.3kGitHub starsopen-computer-useAgentAI computer use powered by open source LLMs and E2B Desktop SandboxOpen sourcePython · Apache-2.0Verified 2.3kGitHub starsharmonistFrameworkPortable AI agent orchestration with mechanical protocol enforcement. 186 agents, zero runtime dependencies.Open sourcePython · MITVerified 2.3kGitHub starsagentic_securityAgentAgentic LLM Vulnerability Scanner / AI red teaming kitOpen sourcePython · Apache-2.0Verified · Active 2.0kGitHub starsMCP Memory ServiceMCP serverSelf-hosted persistent memory for Claude and agent pipelines, over MCP, REST, OAuth and CLI.Open sourcePython · Apache-2.0Verified · Active 2.0kGitHub starsDemoGPTFrameworkCreate LLM agents in a second with your prompts. Everything you need to create an LLM Agent - tools, prompts, frameworks, and models - all in one place.Open sourcePython · MITVerified 1.9kGitHub starsShowUIAgent[CVPR 2025] Open-source, End-to-end, Vision-Language-Action model for GUI Agent & Computer Use.Open sourcePython · Apache-2.0Verified 1.9kGitHub starspg-aiguideMCP serverVersion-aware PostgreSQL manual search and best-practice skills that help AI tools write better Postgres code.Open sourcePython · Apache-2.0Verified · Active 1.9kGitHub starsCoreCoderAgentMinimal AI coding agent (~1,000 lines of Python) inspired by Claude Code. Works with any LLM. Think NanoGPT for coding agents. Formerly NanoCoder.Open sourcePython · MITVerified · Active 1.8kGitHub starsGoogle Search Console MCP (mcp-gsc)MCP serverAsk questions of your Google Search Console performance, indexing and URL inspection data.Open sourcePython · MITVerified · Active 1.8kGitHub starsbailingAgentA GPT-4o-like voice conversation robot built from ASR+LLM+TTS, integrating strong models like DeepSeek R1 and openClaw -- a genuine personal voice assistant with latency as low as 800ms.Open sourcePython · MITVerified 1.8kGitHub starsOpenAdaptAgentOpen Source Generative Process Automation (i.e. Generative RPA). AI-First Process Automation with Large ([Language (LLMs) / Action (LAMs) / Multimodal (LMMs)] / Visual Language (VLMs)) ModelsOpen sourcePython · MITVerified · Active 1.8kGitHub starsAuto-Deep-ResearchAgent"Your Fully-Automated Personal AI Assistant"Open sourcePythonVerified 1.7kGitHub starsTelegram MCPMCP serverRead chats, manage groups and send messages from a Telegram account through Claude, Cursor and other MCP clients.Open sourcePython · Apache-2.0Verified · Active 1.7kGitHub starsToolUniverseSDK / libraryDemocratizing AI scientists with ToolUniverseOpen sourcePython · Apache-2.0Verified · Active 1.7kGitHub starsCyberVersePlatformSelf hosted, real-time digital human agent platform. Build voice-first AI agents with WebRTC, persona memory, tools, RAG, and optional digital-human video.Open sourcePython · GPL-3.0Verified · Active 1.7kGitHub starsAgentlyFramework[GenAI Application Development Framework] Build GenAI application quick and easy Easy to interact with GenAI agent in code using structure data and chained-calls syntax Use Event-Driven FlowOpen sourcePython · Apache-2.0Verified · Active 1.7kGitHub starsAdalaFrameworkAdala: Autonomous DAta (Labeling) Agent frameworkOpen sourcePython · Apache-2.0Verified · Active 1.6kGitHub starsMCP Server for WinDbgMCP serverAnalyse Windows crash dumps and debug user-mode or kernel targets in natural language via WinDbg.Open sourcePython · MITVerified · Active 1.6kGitHub starsMiniMax MCPMCP serverOfficial MCP server for MiniMax text-to-speech, voice cloning, image and video generation.Open sourcePython · MITVerified · Active 1.6kGitHub starsQdrant MCP ServerMCP serverQdrant's official MCP server: store and retrieve semantic memories in a Qdrant vector database.Open sourcePython · Apache-2.0Verified · Active 1.5kGitHub starsROS MCP ServerMCP serverConnect Claude, GPT and Gemini to ROS robots for two-way control and observation without changing robot code.Open sourcePython · Apache-2.0Verified · Active 1.5kGitHub starsMySQL MCP ServerMCP serverA Python MCP server for listing, reading and querying MySQL tables through a controlled interface.Open sourcePython · MITVerified 1.4kGitHub starsVoiceModeMCP serverNatural voice conversations with Claude Code and other MCP agents, with optional fully local speech.Open sourcePython · MITVerified · Active 1.4kGitHub starsJupyter MCP ServerMCP serverLet AI agents read, edit and run Jupyter notebooks in real time, locally or in hosted sandboxes.Open sourcePython · BSD-3-ClauseVerified · Active 1.3kGitHub starsTrustRAGFrameworkTrustRAG：The RAG Framework within Reliable input,Trusted outputOpen sourcePythonVerified 1.3kGitHub starsGarmin MCP ServerMCP serverExpose your Garmin Connect activities, health metrics and training data to Claude and other MCP clients.Open sourcePython · MITVerified · Active 1.3kGitHub starsRhinoMCPMCP serverModel geometry and build Grasshopper definitions in Rhino 3D by chatting with Claude or Cursor.Open sourcePython · MITVerified · Active 1.1kGitHub starsColab MCPMCP serverGoogle Colab's MCP server that bridges a local agent to a Colab notebook session in the browser.Open sourcePython · Apache-2.0Verified 1.1kGitHub starsCisco MCP ScannerInfrastructureScan MCP servers and tools for malicious behaviour with YARA rules, LLM analysis and Cisco AI Defense.Open sourcePython · Apache-2.0Verified · Active 1.1kGitHub starsPatterSDK / libraryOpen-source voice-AI SDK. The Vapi/Retell alternative for builders who want to own the stack.Open sourcePython · MITVerified · Active 1.1kGitHub starsarcade-mcpMCP serverMCP Server Framework and Tool Development library for building custom capabilities into agents.Open sourcePython · MITVerified · Active 1.0kGitHub starsGoogle Sheets MCP (mcp-google-sheets)MCP serverCreate, read and modify Google Sheets and find spreadsheets in Drive from any MCP client.Open sourcePython · MITVerified 1.0kGitHub starsMCPM (MCP Manager)InfrastructureA CLI package manager and registry for MCP servers that works across clients, with profiles and a router.Open sourcePython · MITVerified · Active 1.0kGitHub starsspec_driven_developAgentSpec-driven development workflow for AI coding agents: architecture-first planning, task decomposition, GitHub Issue/PR tracking, Deep Discuss, and adaptive control for Claude Code, Codex, Cursor,Open sourcePython · MITVerified 975GitHub starsMCP-BridgeInfrastructureA middleware to provide an openAI compatible endpoint that can call MCP toolsOpen sourcePython · MITVerified 928GitHub starsopenyakAgentOpen-source local-first AI agent for desktop work. No account, no telemetry: use local models with Ollama/Rapid-MLX or bring your own provider key.Open sourcePython · Apache-2.0Verified · Active 703GitHub starssecond-brainFrameworkSecond Brain is an agentic framework that acts as an operating system, using local file intelligence, workflow automation, and LLMs to complete tasks and communicate over multiple modalities andOpen sourcePython · MITVerified · Active 663GitHub starsAgentPilotAgentA versatile workflow automation platform to create, organize, and execute AI workflows, from a single LLM to complex AI-driven workflows.Open sourcePython · AGPL-3.0Verified 567GitHub starsforge-filmAgentMulti-model DAG-driven parallel AI film generation -- parallel speedup scales with scene independence; generates film scenes simultaneously instead of one by one.Open sourcePython · MITVerified 537GitHub starsconciergeSDK / libraryUniversal SDK for building next-gen MCP serversOpen sourcePythonVerified 530GitHub starsJARVISAgentYour own personal voice assistant: Voice to Text to LLM to Speech, displayed in a web interfaceOpen sourcePython · GPL-3.0Verified 528GitHub starsai-avatar-systemAgentAI Avatar / digital human platform — upload a photo, clone a voice, talk to any face in real time with lip-sync video. Open-source, self-hosted. Claude · Whisper · Chatterbox · MuseTalk.Open sourcePython · MITVerified · Active 507GitHub starsDeepgram Python SDKSDK / libraryPython client library for Deepgram APIs; hosted service usage is separate.Open sourcePython · MITVerified · Active 468GitHub starsbolnaAgentEnd-to-end platform for building voice first multimodal agentsOpen sourcePython · MITVerified 433GitHub starssutandoAgentMy AI Stand. Realtime by day, rewriting itself by night. Summon my AI superpower.Open sourcePython · MITVerified · Active 397GitHub starsagent-second-brainAgentAn always-on second brain you talk to. Voice notes in Telegram → typed, linked knowledge in your Obsidian vault. Runs 24/7 on the Claude subscription you already have.Open sourcePython · MITVerified 388GitHub starsLLMVoXSDK / libraryLLMVoX: Autoregressive Streaming Text-to-Speech Model for Any LLMOpen sourcePythonVerified 312GitHub starsopenbrowser-aiFrameworkOpenBrowser is a framework for intelligent browser automation.Open sourcePython · MITVerified · Active 268GitHub starsM.I.L.E.SAgentM.I.L.E.S, a GPT-4-Turbo voice assistant, self-adapts its prompts and AI model, can play any Spotify song, adjusts system and Spotify volume, performs calculations, browses the web and internet,Open sourcePython · MITVerified 236GitHub starsBrowserPilotAgentOpen‑source alternative to Perplexity Comet, director.ai and firecrawl combinedOpen sourcePython · MITVerified 180GitHub starsaxiom-voice-agentAgentRun a <400ms latency Voice Agent on just 4GB VRAM. Fully offline, no API keys required. Optimized for GTX 1650 and edge robotics with zero-copy inference. (Apache 2.0)Open sourcePython · Apache-2.0Verified 147GitHub starsBentoVoiceAgentAgentBuild Phone Calling Voice Agent fully powered by open source models.Open sourcePythonVerified 132GitHub starsAI-Voice-AgentAgentSelf-hosted AI voice agentOpen sourcePython · MITVerified · Active 41GitHub stars
Frequently asked
- What are the best Python AI agents?
- By maintained adoption — GitHub stars plus recent commit activity — Hermes Agent, AutoGPT and Langflow lead the Python AI agents in this index of 166. The full ranking is below; it reflects what is genuinely used and still maintained, not what pays.
- Are these Python AI agents open source and free?
- Yes — every project on this page is open source and written primarily in Python. MIT is the most common licence here, on 84 of 166, across 8 licences in total. The software is free to run and self-host; you still pay for the infrastructure you run it on and any model or API usage it makes.
- Why choose Python AI agents specifically?
- Staying in your team's primary language — Python — makes self-hosting, extending, and debugging far easier, because you can read and modify the source directly instead of treating it as a black box. It also makes upstream activity something you can judge: 135 of these 166 shipped in the last 90 days, and reading a quiet project's source is how you tell finished from abandoned.