Best Python AI agents
The open-source AI agents written in Python, from the Agent Search Engine index — ranked by real maintained adoption (GitHub stars and recent commit activity), never by sponsorship. Every project here is Python-first, self-hostable, and free to run; the trade-off is you host and maintain it yourself.
01AutoGPTAutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on…02langchainThe agent engineering platform.03browser-useMake websites accessible for AI agents. Automate tasks online with ease.04deer-flowAn open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, sub…05ScraplingAn adaptive Web Scraping framework that handles everything from a single request to a full-scale crawl!06TrendRadarAI-driven public opinion & trend monitor with multi-platform aggregation, RSS, and smart alerts. 告别信息过载，你的 AI 舆情监控助手与热点筛选工具！聚合多平台热点 + RS…07mem0Universal memory layer for AI Agents08autogenA programming framework for agentic AI09crewAIFramework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work tog…10CowAgentOpen-source super AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-model, mu…11nanobotLightweight, open-source AI agent for your tools, chats, and workflows.12BettaFish微舆：人人可用的多Agent舆情分析助手，打破信息茧房，还原舆情原貌，预测未来走向，辅助决策！从0实现，不依赖任何框架。
13agnoBuild, run, and manage agent platforms.14wshobson/agentsMulti-harness agentic plugin marketplace for Claude Code, Codex CLI, Cursor, OpenCode, GitHub Copilot, and Gemini CLI15khojYour AI second brain. Self-hostable. Get answers from the web or your docs. Build custom agents, schedule automations, do deep research. Tu…16stormAn LLM-powered knowledge curation system that researches a topic and generates a full-length report with citations.17gpt-researcherAn autonomous agent that conducts deep research on any data using any LLM providers18agenticSeekFully Local Manus AI. No APIs, No $200 monthly bills. Enjoy an autonomous agent that thinks, browses the web, and code for the sole cost of…19serenaA powerful MCP toolkit for coding, providing semantic retrieval and editing capabilities - the IDE for your agent20fastmcpThe fast, Pythonic way to build MCP servers and clients.21skyvernAutomate browser based workflows with AI22MaxKBMaxKB is an open-source platform for building enterprise-grade agents. 强大易用的开源企业级智能体平台。23DeepResearchTongyi Deep Research, the Leading Open-source Deep Research Agent24FunASRIndustrial-grade speech recognition toolkit: 170x realtime, 50+ languages, speaker diarization, emotion detection, streaming, and OpenAI-co…25pydantic-aiAI Agent Framework, the Pydantic way26SuperAGI<> SuperAGI - A dev-first open source autonomous AI agent framework. Enabling developers to build, manage & run useful autonomous agents…27Skill_SeekersConvert documentation websites, GitHub repositories, and PDFs into Claude AI skills with automatic conflict detection28Agent-SAgent S: an open agentic framework that uses computers like a human29fastapi_mcpExpose your FastAPI endpoints as Model Context Protocol (MCP) tools, with Auth!30agent-frameworkA framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and.NET.31hiveMulti-Agent Harness for Production AI32hexstrike-aiHexStrike AI MCP Agents is an advanced MCP server that lets AI agents (Claude, GPT, Copilot, etc.) autonomously run 150+ cybersecurity tool…33ida-pro-mcpAI-powered reverse engineering assistant that bridges IDA Pro with language models through MCP.34AWS MCP ServersOpen source MCP Servers for AWS35local-deep-research~95% on SimpleQA (e.g. Qwen3.6-27B on a 3090). Supports all local and cloud LLMs (llama.cpp, Ollama, Google,...). 10+ search engines - arX…36MiroThinkerMiroThinker is a deep research agent optimized for complex research and prediction tasks. Our latest models, MiroThinker-1.7, achieves 74.0…37deep-searcherOpen Source Deep Research Alternative to Reason and Search on Private Data. Written in Python.38UpsonicBuild autonomous AI agents in Python.39ShortGPTShortGPT - Experimental AI framework for youtube shorts / tiktok channel automation40BinduBindu: The identity, communication, and payments layer for AI agents.41unstractLLM-Driven Extraction of Unstructured Data — Built for API Deployments & ETL Pipeline Workflows42openevolveOpen-source implementation of AlphaEvolve43intentkitIntentKit is an open-source, self-hosted cloud agent cluster that manages a collaborative team of AI agents for you.44harness-sdkBuild an agent harness and control it end-to-end. Open-source SDK for production AI agents in Python & TypeScript - any model, any cloud.45faraFara-7B: An Efficient Agentic Model for Computer Use46agentsAn Open-source Framework for Data-centric, Self-evolving Autonomous Language Agents47klavisKlavis AI: MCP integration platforms that let AI agents use tools reliably at any scale48rllmDemocratizing Reinforcement Learning for LLMs49sembleFast and Accurate Code Search for Agents. Uses ~98% fewer tokens than grep+read50ag2AG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3x51agents-cliThe CLI and skills that turn any coding assistant into an expert at creating, evaluating, and deploying AI agents on Google Cloud.52agent-governance-toolkitAI Agent Governance Toolkit — Policy enforcement, zero-trust identity, execution sandboxing, and reliability engineering for autonomous AI…53youtu-agentA simple yet powerful agent framework that delivers with open-source models54ms-agentMS-Agent: a lightweight framework to empower agentic execution of complex tasks55DeepAnalyzeDeepAnalyze is the first agentic LLM for autonomous data science. 你的AI数据分析师，自动分析大量数据，一键生成专业分析报告！56mcpoA simple, secure MCP-to-OpenAPI proxy server57excel-mcp-serverA Model Context Protocol server for Excel file manipulation58fast-agentCode, Build and Evaluate agents - excellent Model and Skills/MCP/ACP/A2A Support59claude_codex_bridgeVisible multi-agent CLI workspace for mixing Codex, Claude, Gemini, Kimi, Qwen, Cursor, Copilot, Pi, OpenCode, and other AI coding agents60TuriX-CUAThis is the official website for TuriX Computer-use-Agent61MiroFlowTop-1 on 5+ benchmarks | Web UI | Supports MiroThinker, Claude, Kimi, OpenAI62teaql-agent-kitDeterministic execution for non-deterministic AI.63Vibe-SkillsVibe-Skills is an all-in-one AI skills package. It seamlessly integrates expert-level capabilities and context management into a general-pu…64cocoindex-codeA super light-weight embedded code search engine CLI (AST based) that just works - saves 70% token and improves speed for coding agent S…65harmonistPortable AI agent orchestration with mechanical protocol enforcement. 186 agents, zero runtime dependencies.66open-computer-useAI computer use powered by open source LLMs and E2B Desktop Sandbox67verl-agentverl-agent is an extension of veRL, designed for training LLM/VLM agents via RL. verl-agent is also the official code for paper "Group-in-G…68agentic_securityAgentic LLM Vulnerability Scanner / AI red teaming kit69DemoGPTCreate LLM agents in a second with your prompts. Everything you need to create an LLM Agent - tools, prompts, frameworks, and models - a…70ShowUI[CVPR 2025] Open-source, End-to-end, Vision-Language-Action model for GUI Agent & Computer Use.71bailing百聆 是一个类似GPT-4o的语音对话机器人，通过ASR+LLM+TTS实现，集成DeepSeek R1等优秀大模型，接入openClaw，真正的个人语音助手，时延低至800ms，Mac等低配置也可运行，支持打断72OpenAdaptOpen Source Generative Process Automation (i.e. Generative RPA). AI-First Process Automation with Large ([Language (LLMs) / Action (LAMs) /…73Agently[GenAI Application Development Framework] Build GenAI application quick and easy Easy to interact with GenAI agent in code using stru…74AdalaAdala: Autonomous DAta (Labeling) Agent framework75Auto-Deep-Research"Your Fully-Automated Personal AI Assistant"76ToolUniverseDemocratizing AI scientists with ToolUniverse77CoreCoderMinimal AI coding agent (~1,000 lines of Python) inspired by Claude Code. Works with any LLM. Think NanoGPT for coding agents. Formerly Nan…78CyberVerseSelf hosted, real-time digital human agent platform. Build voice-first AI agents with WebRTC, persona memory, tools, RAG, and optional digi…79TrustRAGTrustRAG：The RAG Framework within Reliable input,Trusted output80arcade-mcpMCP Server Framework and Tool Development library for building custom capabilities into agents.81MCP-BridgeA middleware to provide an openAI compatible endpoint that can call MCP tools82PatterOpen-source voice-AI SDK. The Vapi/Retell alternative for builders who want to own the stack. Give your AI agent a phone number in 4 lines…83spec_driven_developSpec-driven development workflow for AI coding agents: architecture-first planning, task decomposition, GitHub Issue/PR tracking, Deep Disc…84openyakOpen-source local-first AI agent for desktop work. No account, no telemetry: use local models with Ollama/Rapid-MLX or bring your own provi…85forge-filmMulti-model DAG-driven parallel AI film generation — parallel speedup scales with scene independence; Generate film scenes simultaneously i…86second-brainSecond Brain is an agentic framework that acts as an operating system, using local file intelligence, workflow automation, and LLMs to comp…87AgentPilotA versatile workflow automation platform to create, organize, and execute AI workflows, from a single LLM to complex AI-driven workflows.88conciergeUniversal SDK for building next-gen MCP servers89JARVISYour own personal voice assistant: Voice to Text to LLM to Speech, displayed in a web interface90deepgram-python-sdkOfficial Python SDK for Deepgram.91bolnaEnd-to-end platform for building voice first multimodal agents92sutandoMy AI Stand. Realtime by day, rewriting itself by night. Summon my AI superpower.93LLMVoXLLMVoX: Autoregressive Streaming Text-to-Speech Model for Any LLM94ai-avatar-systemAI Avatar / digital human platform — upload a photo, clone a voice, talk to any face in real time with lip-sync video. Open-source, self…95agent-second-brainAn always-on second brain you talk to. Voice notes in Telegram → typed, linked knowledge in your Obsidian vault. Runs 24/7 on the Claude su…96openbrowser-aiOpenBrowser is a framework for intelligent browser automation. It combines direct CDP communication with a CodeAgent architecture, where th…97M.I.L.E.SM.I.L.E.S, a GPT-4-Turbo voice assistant, self-adapts its prompts and AI model, can play any Spotify song, adjusts system and Spotify volum…98BrowserPilotOpen‑source alternative to Perplexity Comet, director.ai and firecrawl combined99AI-Voice-AgentSelf-hosted AI voice agent100axiom-voice-agentRun a <400ms latency Voice Agent on just 4GB VRAM. Fully offline, no API keys required. Optimized for GTX 1650 and edge robotics with zero-…101BentoVoiceAgentBuild Phone Calling Voice Agent fully powered by open source models.
Frequently asked
- What are the best Python AI agents?
- The Python projects listed below, ranked by maintained adoption — GitHub stars plus recent commit activity — so you see what's genuinely used and still maintained, not abandoned.
- Are these Python AI agents open source and free?
- Yes — every project on this page is open source and written primarily in Python. The software is free to run and self-host; you still pay for the infrastructure you run it on and any model or API usage it makes.
- Why choose Python AI agents specifically?
- Staying in your team's primary language — Python — makes self-hosting, extending, and debugging far easier, because you can read and modify the source directly instead of treating it as a black box.